Principal Investigator

Susan Kaech
Professor and Director
Nomis Center for Immunobiology and Microbial Pathogenesis
Nomis Foundation Chair
Ph.D. Developmental Biology, Stanford University
The West coast is the best coast. I love spending time outside under the California sun, whether on a hike or while enjoying the sunset with a nice glass of wine. It is even better when I can do it with my loving family and friends. I also enjoy multicolor flow cytometry and cooking.
Research Associates

Dan Chen
Research Associate
Ph.D. Biology, Nanjing University
Dan’s study is focused on the mechanisms of resistance to immunotherapy in PDX and glioblastoma models. Her goal is to bolster the immune system against tumors. Outside the lab, she enjoys swimming and travel.

Hokyung “Kay” Chung
Research Associate
Kay focuses on how CD8+ T cell states are determined by their internal (transcription factors) and external (environmental cues) programmers to design “smarter” T cells. Outside of the lab, she enjoys walking her dog Oli and exploring the best coffee roasters in San Diego.

Victor Du
Research Associate
M.S. Biology, Georgia Institute of Technology
Ph.D. Microbiology, University of Alabama at Birmingham
Victor’s research focuses on the majestic natural killer (NK) cells and how to fine tune these immune cells to effectively target tumors that are resistant to T cells. In his free time, he likes hiking, reading, and grabbing good beers with friends.

Yagmur Farsakoglu
Research Associate
Ph.D. Immunology, Bern University & Institute for Research in Biomedicine
Yagmur is interested in elucidating the effects of pro-/anti-inflammatory mediators on regulating the spatiotemporal dynamics of CD8+ T cell fate determination in secondary lymphoid organs. She enjoys reading books, drinking good wine and watching movies.

Anna-Maria Globig
Research Associate
Anna aims to understand how the function of T cells can be metabolically manipulated in the context of different autoimmune diseases and in T cell exhaustion. Outside of lab, she enjoys exploring the Californian outdoors.

Shixin Ma
Research Associate
Ph.D. Immunology, Institut Pasteur of Shanghai
Shixin is focusing on the metabolic influence on the epigenetic landscape of CD8+ T cells within the tumor microenvironment. She enjoys traveling during her free time.

Tom Mann
Research Associate
Ph.D. Biochemistry, Stanford University
Tom is studying the dynamics of intracellular calcium signaling in T cell exhaustion. Outside of lab, he enjoys board games, juggling, and tennis.

Annelise Snyder
Research Associate
Ph.D. Immunology, University of Washington
Annelise is interested in examining how immunometabolism influences the pathogenesis of neurodegenerative disorders. Outside of lab, she enjoys rooting for the Patriots and exploring the outdoors with her dog.

Karthik Varanasi
Research Associate
M.Sc. Biotechnology, Vellore Institute of Technology
Ph.D. Genome Science and Technology, University of Tennessee
“Change brings faster results than chance.” My research focuses on how immune cells change their metabolism within different tissues to fit the local environment to stay functional.

Shihao Xu
Research Associate
Ph.D. Biochemistry, University of Rochester
I am interested in metabolic regulation of anti-tumor immunity, CD8+ T cell function in particular. By harnessing transgenic mouse models and in vitro immunological tools, we hope to gain a better understanding of how deregulated lipid metabolism contributes to CD8+ T cell dysfunction.

Steven Zhao
Research Associate
Ph.D. Cell & Molecular Biology, University of Pennsylvania
Steve is interested in how the nutrient environment of cells affects cellular metabolism and function. The goal of his research is to understand how altered metabolic states in diseases such as obesity and cancer influence the immune compartment. Outside of the lab, he enjoys anything food related, tennis, and photography.
Staff Researcher

Hubert Tseng
Senior Staff Researcher
Ph.D. Bioengineering, Rice University
Hubert is currently focused on single cell cytokine analysis to profile the functional diversity of immune cells in tumor microenvironments. Outside of lab, he really likes to eat.

Research Assistants



Patricia Rodriguez Morales
Research Assistant
Patricia’s research is focused on understanding the cellular and molecular basis of increased cancer incidence among patients with chronic viral infections (e.g. HIV). Her goal is to better understand how the chronic viral setting affects anti-tumor immunity. Outside of lab she likes to take long walks, try new places to eat, and spend time with family and friends.

Kacie Traina
Research Assistant
Kacie is focused on generating PDX mouse models to uncover molecular mechanisms that control the generation of memory T cells and immunological memory. In her spare time, she enjoys baking and going to the beach.
Graduate Students



Ali Kuhlmann
Graduate Student, Yale University
Ali is currently studying how resident macrophage homeostatic programs can be co-opted during tumorigenesis to aid in the formation of a tolerant immune response. She is specifically focusing on alveolar macrophage lipid and surfactant homeostasis in lung adenocarcinoma.

Bryan McDonald
Graduate Student
Bryan is interested in understanding how extracellular cues influence the cell fate decisions made by CD8 T cells during acute viral infections and in cancer. Outside of lab, he enjoys drinking coffee, eating pastries, and rock climbing.

Ziyan Xu
Graduate Student, University of California, San Diego
Zoe’s interested in understanding the tumor microenvironment, especially the correlation between metabolic changes and functionality in immune cells. She enjoys spending time with her dog Tinkerbell in her spare time.
Lab Technicians
Lab Coordinator

Victoria Tripple
Lab Coordinator
B.A. Psychology, University of California, San Diego
Victoria currently manages the Kaech Lab and also works on in vivo cancer models and infiltrating immune cells. In her spare time, she enjoys taking her son to the zoo and the beach.